Programmable RNA Export

Remarkable new technology from the lab of Prof. Michael Elowitz, California Institute of Technology, permits engineered transfer of synthetic RNA from one cell to another. 

This approach, that they have appropriately called "COURIER" (controlled output and uptake of RNA for interrogation, expression, and regulation), has the potential to elicit complex cell-cell interactions in multi-cellular systems, to modify recipient cell biology and to deliver therapeutic messages following cell homing to distant sites! 

Sincere thanks to the authors for choosing DRAQ7™ to determine the toxicity of their system's elements. Where to buy?

Reference:

Horns et al., Engineering RNA export for measurement and manipulation of living cells, Cell (2023). https://doi.org/10.1016/j.cell.2023.06.013