Thursday, 18 February 2016

AMAZING! 5-Day imaging of Drosophila embryos with CyGEL

This is remarkable! 

The lab of Martin Wasser at A*STAR in Singapore has generated beautiful 5-day time-lapse microscopy videos of developing Drosophila embryos in CyGEL(TM).

For the first time (we believe) this conveniently allows a longitudinal examination of the development of embryos at high resolution to better understand their development and how that is affected by perturbations like siRNAs, drug treatments and so on.

WHERE TO BUY

See more here:
A model of muscle atrophy based on live microscopy of muscle remodelling in Drosophila metamorphosis.
Yadav Kuleesha, Wee Choo Puah, Martin Wasser
Royal Society Open Science. 
Published online February 10, 2016. 
DOI: 10.1098/rsos.150517

http://dx.doi.org/10.1098/rsos.150517

n.b. their detailed method is dealt with in earlier publications.

Here's an example of an embryo in CyGEL, a still from a video created by Judith Callaghan, Monash University...  You can see the brief video here: https://youtu.be/IMTe1Z3q5OE


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