Tuesday 15 September 2015

BioStatus Newsletter September 2015

Smart Apps
Quick and easy "fix and stain" method for HCS


Combined fix & stain method for high content screening:-

Simply mix 8% formaldehyde and 10µM DRAQ5™ for a one-step procedure that reduces pipetting and sample preparation times


See Protocol 3b in the DRAQ5™ technical datasheet

Featured Articles
What's exciting us at BioStatus

A powerful, simple method for radiation biodosimetry in a mass casualty radiological event:-

Automated micronucleus detection using DRAQ5™ and the Merck Millipore ImageStreamX 


REF: Rodrigues et al. Rad. Env. Biophys. 53 (2014) 273-282

Order DRAQ5™ HERE
Key Techniques
Real-time cell health monitoring, cell by cell, in 2D and 3D - in the far-red!

DRAQ7™ is the perfect viability dye for 2-D cell culture, spheroids, explant culture, subcutaneous injection and many more apoptosis/cell health oriented applications.

DRAQ7™ labels only (damaged, dying and dead) membrane-compromised cells and, importantly, red excitation minimises risk of DNA damage when capturing time-lapse images whilst reliably monitoring viability in real-time, cell-by-cell.


Download the latest WHITE PAPER HERE
Read All About Us
What our customers really think of BioStatus products

Read independent reviews here:

DRAQ5™ - proven far-red fluorescent DNA dye for LIVE or fixed cell analysis

DRAQ7™ - far-red fluorescent DNA dye the ONLY stains the nuclei of dead and permeabilised cells
CyGEL™ - a novel thermoreversible gel that is compatible with LIVE cells and organisms
CyGEL Sustain™ - a novel thermoreversible gel for extended imaging of LIVE cells and zebrafish embryos
Focus On...
Flow Cytometry

BioStatus products are proven problem solvers for flow cytometry. Reduce sample preparation, gate on nucleated cells and avoid unwanted and time consuming RBC lysis.

See links to dedicated flow cytometry application notes below:-

  • DRAQ5™ - directly measure DNA content: on whole blood, bone marrow etc...
  • CyTRAK Orange™ - avoid RBC lysis
  • DRAQ7™ - simplify sample quality analysis: dead cell enumeration
 
Product Spotlight
CyGEL™

CyGEL™ is a novel thermoreversible gel that is compatible with LIVE cells and organisms. It can be used to immobilise non-adherent cells and beads by simple warming and conversely allowing their recovery by simple cooling.

Check out our NEW application note below, which discusses sorting intact, living cells immobilised into CyGEL™ onto slides or wells for high resolution imaging:-

CyGEL™ in Cell Sorting
and Finally...


Where to see us
BioStatus supports a wide range of local and international conferences in cytometry, fluorescence microscopy and drug discovery. See these blog pages for “events”



Extra Resources
Visit the BioStatus website – we’ve got a wide collection of resources including application and product specific bibliographies, application notes, videos, posters and more